QUESTION IMAGE
Question
you are conducting a genetic screen using caenorhabditis elegans embryos to isolate mutations affecting anaphase (a). therefore, you need to look for embryos in which
multiple choice
○ the poles do not move apart.
○ sister chromatids are mismatched and therefore fail to separate.
○ the spindle apparatus does not disassemble.
○ the centromeres do not move toward the poles.
Anaphase A is defined by the movement of sister chromatids (attached at centromeres) toward opposite spindle poles via shortening of kinetochore microtubules. Mutations affecting Anaphase A would disrupt this centromere/poleward movement. The other options relate to Anaphase B (pole separation) or later mitotic stages.
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the centromeres do not move toward the poles.