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QUESTION IMAGE

you are conducting a genetic screen using caenorhabditis elegans embryo…

Question

you are conducting a genetic screen using caenorhabditis elegans embryos to isolate mutations affecting anaphase (a). therefore, you need to look for embryos in which

multiple choice

○ the poles do not move apart.

○ sister chromatids are mismatched and therefore fail to separate.

○ the spindle apparatus does not disassemble.

○ the centromeres do not move toward the poles.

Explanation:

Brief Explanations

Anaphase A is defined by the movement of sister chromatids (attached at centromeres) toward opposite spindle poles via shortening of kinetochore microtubules. Mutations affecting Anaphase A would disrupt this centromere/poleward movement. The other options relate to Anaphase B (pole separation) or later mitotic stages.

Answer:

the centromeres do not move toward the poles.