Question

which of the following is not a multiple gene inherited disorder?
a cleft - lip
b spina bifida
c tay - sachs disease
d hydrocephalus

Explanation:

• Cleft - lip: It is a multiple - gene inherited disorder. Environmental factors also play a role in its occurrence.
• Spina bifida: It is a neural tube defect and is a multiple - gene inherited disorder.
• Tay - Sach's disease: It is an autosomal recessive single - gene disorder (caused by mutations in the \(HEXA\) gene).
• Hydrocephalus: It can be a multiple - gene inherited disorder.

Answer:

C. Tay - Sach's disease