Question

where is pyruvate dehydrogenase located?
i dont know yet
in the cytosol of both prokaryotes and eukaryotes
in the mitochondrial matrix of eukaryotes
in the cytosol of prokaryotes and eukaryotes but not in prokaryotes
in the intermembrane space in eukaryotes

Explanation:

Pyruvate dehydrogenase is an enzyme complex that plays a key role in cellular respiration. In eukaryotes, it is located in the mitochondrial matrix. Prokaryotes do not have mitochondria, but in eukaryotes, the mitochondrial matrix is the site for this enzyme complex as it is involved in the conversion of pyruvate to acetyl - CoA, which then enters the citric acid cycle (also in the mitochondrial matrix).

Answer:

In the mitochondrial matrix of eukaryotes