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Question
what is the underlying cause of sickle cell disease? multiple choice a deficiency in intrinsic factor overproduction of hemoglobin a genetic mutation a deficiency in dietary iron
Sickle - cell disease is caused by a genetic mutation in the gene that codes for the beta - globin subunit of hemoglobin. This mutation leads to abnormal hemoglobin (hemoglobin S) which causes red blood cells to sickle. A deficiency in intrinsic factor is related to vitamin B12 absorption problems, overproduction of hemoglobin is not the cause of sickle - cell disease, and a deficiency in dietary iron causes iron - deficiency anemia.
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C. A genetic mutation