Question

sickle cell anemia
normal red
blood cell
sickle cell
hemoglobin beta chain
in sickle cell
normal cell
sickle cell
what type of mutation error has occurred to cause the disorder shown? (1 point)

Explanation:

To determine the mutation causing sickle cell anemia, we analyze the DNA and amino acid sequences. In the normal DNA (CTC/GAG), the codon codes for Glu (glutamic acid). In the sickle cell DNA (CAC/GTG), the codon now codes for Val (valine). This is a point mutation (specifically a substitution mutation), where one nucleotide base is replaced (T in CTC is replaced by A in CAC, or A in GAG is replaced by T in GTG), leading to a single amino acid change in the hemoglobin beta chain. This single - base substitution alters the protein structure, causing red blood cells to sickle.

Answer:

The mutation error is a point mutation (specifically a substitution mutation), where a single nucleotide base is replaced in the DNA sequence, leading to a change in one amino acid (Glu to Val) in the hemoglobin beta chain.