Question

question 15
original dna: tac cta gga cca act has changed to tac cta gac caa ct.
what type of mutation has occurred, and has it caused a frameshift?
a insertion - no
b deletion - yes
c translocation - yes
d substitution - no

Explanation:

• Insertion/deletion/translocation vs substitution:
• Insertion is adding nucleotides. Deletion is removing nucleotides. Translocation is swapping parts between non - homologous chromosomes. Substitution is replacing one nucleotide with another.
• Original DNA: TAC CTA GGA CCA ACT (15 nucleotides). Mutated DNA: TAC CTA GAC CAA CT (13 nucleotides). So, nucleotides are removed (deletion).
• Frameshift mutation:
• A frameshift mutation occurs when nucleotides are inserted or deleted (not in multiples of 3). Since nucleotides are deleted (not in multiples of 3), it causes a frameshift.

Answer:

b. deletion - yes