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Question
parietal cells antibodies can cause a conditon in which your rbcs become:
a) stacked like coins
b) clumped together
c) nucleated
d) larger
e) smaller
Parietal cell antibodies are associated with pernicious anemia, where vitamin B12 deficiency leads to megaloblastic anemia. In this condition, red blood cells (RBCs) become larger (macrocytic) due to impaired DNA synthesis. Option a (stacked like coins) is rouleaux, option b (clumped) is agglutination, option c (nucleated) is not typical for mature RBCs in this context, option e (smaller) is microcytic (e.g., iron deficiency). So the correct answer relates to RBCs becoming larger.
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d) larger