QUESTION IMAGE
Question
the genetic condition analyzed in the following pedigree could be an autosomal dominant condition.
Brief Explanations
In an autosomal dominant condition, an affected individual has at least one affected parent (assuming no new mutations). Looking at the pedigree:
- Generation I: Individual 2 (affected). Her offspring (Generation II - 1) is unaffected. If it were autosomal dominant, and assuming individual 2 has a genotype like \(Aa\) (where \(A\) is the dominant allele), there is a 50% chance of passing the \(A\) allele. But the key is that in Generation III, there are affected individuals (III - 2 and III - 3). However, if we assume autosomal dominant, we can check the pattern. Let's assume the allele for the condition is \(A\) (dominant) and \(a\) (recessive).
- Generation II - 1 (unaffected, genotype \(aa\)) and Generation II - 2 (unaffected, genotype \(aa\)) would need to pass on an \(A\) allele to have affected offspring (III - 2 and III - 3) if it were autosomal dominant, which is not possible as they are \(aa\). So it cannot be autosomal dominant.
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False