Question

drag each tile to the correct location on the table.

classify the mutations as somatic or inherited.

somatic mutations | inherited mutations

tiles:

• mutations of the braf gene in skin cells promote uncontrolled cell division.
• mutations of the brca1 gene in egg cells lead to breast cancer.
• mutations in the frg2 gene in sperm cells lead to loss of muscle mass.
• mutations in the kras gene in lung cells promote continuous cell growth.

Explanation:

Classify mutations in body cells as somatic

Somatic mutations occur in non-reproductive body cells (e.g., skin cells, lung cells) and are not passed to offspring.

• Mutations of the BRAF gene in skin cells promote uncontrolled cell division.
• Mutations in the KRAS gene in lung cells promote continuous cell growth.

Classify mutations in germline cells as inherited

Inherited (germline) mutations occur in reproductive cells (e.g., egg cells, sperm cells) and can be passed to offspring.

• Mutations of the BRCA1 gene in egg cells lead to breast cancer.
• Mutations in the FRG2 gene in sperm cells lead to loss of muscle mass.

Answer:

Somatic Mutations	Inherited Mutations
Mutations in the KRAS gene in lung cells promote continuous cell growth.	Mutations in the FRG2 gene in sperm cells lead to loss of muscle mass.