QUESTION IMAGE
Question
cystic fibrosis is a genetic condition. the diagram shows the genetic mutation that results in cystic fibrosis.
cystic fibrosis gene sequence
nucleotide atc atc ttt ggt gtt
amino acid ile ile phe gly val
506 508 510
deleted
mutated gene sequence
nucleotide atc att ggt gtt
amino acid ile ile gly val
506
what is the result of the mutation shown on the cystic fibrosis protein formed?
the protein will be the same.
the protein will have a different structure so it will function differently.
the protein will be larger in size.
the protein will be effective only in large quantities.
In the original gene sequence, there was a nucleotide sequence (CTC TTT) coding for Phe at position 508. After mutation (deletion), this amino - acid is missing. Since the structure of a protein (primary structure is the sequence of amino - acids) determines its function, a change in the amino - acid sequence (loss of Phe at 508) will lead to a different protein structure. Different protein structures have different functions. The protein is not the same (as an amino - acid is deleted), it is not larger (an amino - acid is removed, not added), and there is no indication that it will be effective only in large quantities.
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The protein will have a different structure so it will function differently.