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although we may never know the exact magnitudes of the depopulation, it is estimated that upwards of 80 - 95 percent of the native american population was decimated within the first 100 - 150 years following 1492. - nathan nunn and nancy qian, journal of economic perspectives, spring 2010 the main reason for the loss of lives described in the excerpt is that american indians a were shipped to europe as slaves b experienced a series of famines c exhausted their supplies of natural resources d were not immune to european diseases
After 1492, when Europeans came to the Americas, they brought diseases like smallpox. Native Americans had no immunity to these European - introduced diseases. Slavery of Native Americans to Europe was not a major cause of the large - scale population decline as described. Famines and exhaustion of natural resources were not the main reasons for the extreme population loss compared to the impact of new - introduced diseases.
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D. were not immune to European diseases