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huntingtons disease is a genetic disease that strikes during middle age and leads to massive degeneration of the basal ( 1. ) and later of the cerebral cortex. its initial symptoms in many patients are wild, jerky, and almost continuous flapping movements called chorea (greek for “dance”). although the movements appear to be voluntary, they are not. late in the disease, marked mental ( 2. ) occurs, resulting in a lack of focus, fatigue, and irritability. huntingtons disease is progressive, and the prognosis varies from 10 to 30 years from the onset of symptoms.
the signs and symptoms of early huntingtons disease are essentially the ( 3 ) of parkinsons disease (overstimulation rather than inhibition of the motor drive), and huntingtons is usually treated with drugs that block, rather than enhance, ( 4. ) effects. late in the disease, however, dopamine levels fall below normal levels, as seen in parkinsons patients. as with parkinsons, fetal tissue or ( 5 ) cell implants may help huntingtons patients in the future.
as you can see, neurotransmitters, which are the “vocabulary” of neurons, can cause garbled neural language when things go wrong.
o 1 deterioration 2. opposite 3 dopamines 4 stem 5 nuclei
o 1. stem 2. nuclei 3. deterioration 4 opposite 5. dopamines
o 1 nuclei 2 deterioration 3 opposite 4. dopamines 5. stem
o 1 dopamines 2. stem 3 nuclei 4 deterioration 5 opposite
o 1 opposite 2 dopamines 3 stem 4 nuclei 5 deterioration
- Huntington's disease leads to massive degeneration of the basal nuclei, so "nuclei" fits for (1).
- Late - stage symptoms include marked mental deterioration, so "deterioration" for (2).
- Early symptoms of Huntington's are opposite of Parkinson's, so "opposite" for (3).
- Huntington's is usually treated with drugs that block dopamine's effects, so "dopamine's" for (4).
- Fetal tissue or stem cell implants may help in the future, so "stem" for (5).
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- nuclei 2. deterioration 3. opposite 4. dopamine's 5. stem