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Question
write down the causes of microcytic and macrocytic anemia:
Microcytic anemia is often caused by iron deficiency (common in inadequate dietary intake, chronic blood loss like from menstruation or gastrointestinal bleeding), thalassemia (genetic disorder affecting hemoglobin synthesis), and lead poisoning (interferes with heme synthesis). Macrocytic anemia can result from vitamin B12 deficiency (due to pernicious anemia - autoimmune destruction of parietal cells in the stomach that secrete intrinsic factor needed for B12 absorption, or dietary deficiency especially in vegetarians), folate deficiency (poor diet, alcoholism - as alcohol impairs folate absorption and metabolism), and certain medications (e.g., some antiretrovirals, chemotherapy drugs that affect DNA synthesis in red blood cell precursors).
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Microcytic anemia causes: iron deficiency (dietary, blood loss), thalassemia, lead poisoning. Macrocytic anemia causes: vitamin B12 deficiency (pernicious anemia, dietary), folate deficiency (diet, alcoholism), some medications.