Question

the state in which the body is poisoned by alcohol or another substance and the persons physical and mental control is significantly reduced.

drunk
intoxication
infiltrated
fatigued

Explanation:

The definition describes a state of bodily poisoning by alcohol/substances with reduced physical/mental control. "Drunk" refers only to alcohol-induced impairment, "Infiltrated" means permeation, and "Fatigued" means tiredness. "Intoxication" precisely matches the given definition.

Answer:

Intoxication