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Question
question 8 (mandatory) (10 points)
cystic medial necrosis of the aorta is associated with which of the following?
syphilitic aortitis
polyarteritis nodosa
atherosclerosis
marfan syndrome
bacterial endocarditis
Cystic medial necrosis of the aorta is a pathological change in the aortic media. Marfan syndrome is a genetic disorder that affects the connective tissue. In Marfan syndrome, there are defects in the fibrillin - 1 protein, which leads to abnormal elastic fiber formation in the aortic media. This results in cystic medial necrosis. Syphilitic aortitis is associated with inflammation due to syphilis infection (not cystic medial necrosis). Polyarteritis nodosa is a necrotizing vasculitis of medium - sized arteries (not specifically related to aortic cystic medial necrosis). Atherosclerosis is related to lipid deposition in the intima. Bacterial endocarditis is an infection of the endocardium (not directly related to aortic cystic medial necrosis).
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Marfan syndrome