Question

for parenteral drugs (injection or inhalation), the slides state that:

select one:
a. all microorganisms are considered objectionable
b. only yeast are objectionable
c. microbes are filtered by the immune system first
d. microbes are harmless by default

Explanation:

Analyze parenteral drug requirements

Parenteral drugs bypass highly protective mucosal and digestive barriers of the body, entering directly into systemic circulation or deep tissues. Therefore, they must be completely sterile, meaning any and all microorganisms present are considered objectionable.

Evaluate the options

• Option a: Correct, because parenteral administration requires absolute sterility, making any microbial presence objectionable.
• Option b: Incorrect, as bacteria, molds, and viruses are also highly objectionable.
• Option c: Incorrect, the immune system does not act as a physical filter before systemic distribution of injected contaminants.
• Option d: Incorrect, microbes introduced parenterally can cause severe systemic infections or pyrogenic reactions.

Answer:

• a. All microorganisms are considered objectionable (Correct answer)
• b. Only yeast are objectionable
• c. Microbes are filtered by the immune system first
• d. Microbes are harmless by default