Question

a nurse is caring for a client who is to receive treatment for opioid use disorder. which of the following medications should the nurse expect to administer?

bupropion
disulfiram
modafinil
methadone

Explanation:

Analyze the clinical indication

The question asks for a medication used to treat a client with opioid use disorder (OUD). Treatment for OUD typically involves opioid agonists (e.g., methadone), partial agonists (e.g., buprenorphine), or antagonists (e.g., naltrexone) to reduce withdrawal symptoms, cravings, and illicit drug use.

Evaluate the options

• Bupropion: An atypical antidepressant primarily used for major depressive disorder and smoking cessation support. It is not indicated for opioid use disorder.
• Disulfiram: An aldehyde dehydrogenase inhibitor used as an alcohol antagonist therapy for chronic alcohol use disorder. It causes highly unpleasant physical reactions when alcohol is consumed, but has no role in treating opioid use disorder.
• Modafinil: A central nervous system stimulant used to promote wakefulness in conditions like narcolepsy, shift work sleep disorder, and obstructive sleep apnea. It is not used for opioid use disorder.
• Methadone: A long-acting synthetic mu-opioid receptor full agonist. It is widely used for detoxification and maintenance therapy in individuals with opioid use disorder to prevent withdrawal symptoms and reduce cravings without producing euphoria when administered in controlled therapeutic doses.

Determine the correct medication

Based on pharmacological indications, methadone is the correct medication among the choices provided for the treatment of opioid use disorder.

Answer:

• (A) Bupropion
• (B) Disulfiram
• (C) Modafinil
• (D) Methadone (Correct answer)