Question

note: human subjects were divided into three groups: group 1 received drug l after ceasing administration of drug e, group 2 received a placebo after ceasing administration of drug e, and group 3 did not cease administration of drug e. symptom levels were rated at baseline (bl), and at 1 and 4 weeks. which group(s) had an overall change in rating from baseline to week 4 within 0.5 for each of the four symptoms? a. group 1 only b. group 2 c. group 3 only d. groups 1 and 3

Explanation:

Step1: Observe each graph

Check the change in rating from baseline (BL) to Week 4 for each group in all four - symptom graphs.

Step2: Analyze Group 1

In Group 1, for each of the four symptoms (Desire for Drug E, Restlessness, Total Self - Reported Symptoms, Nervousness, Irritability), the change in rating from baseline to Week 4 is within 0.5.

Step3: Analyze Group 2

Group 2 shows more significant changes in ratings for some symptoms from baseline to Week 4, exceeding 0.5 in some cases.

Step4: Analyze Group 3

Group 3 also shows changes in ratings that are not all within 0.5 from baseline to Week 4 for all symptoms.

Answer:

A. Group 1 only