Question

mr. chenyi is a 39 - year - old man who recently emigrated to the united states from tibet. during a visit to his physician, he reported a history of bilateral knee and ankle pain. magnetic resonance imaging (mri) showed deformities of his knee joints and narrowed joint spaces in both ankles. given his medical history, country of origin, and radiographic findings, his physician suspects ________. multiple choice
keshan disease
wilson disease
kashin - beck disease
secondary hemochromatosis

Explanation:

Kashin - Beck disease is an endemic osteoarthropathy associated with selenium deficiency, common in regions like Tibet. The patient's joint deformities, narrowed joint spaces, and origin from Tibet match this disease. Kaschin disease is the same as Kashin - Beck disease (sometimes named differently). Wilson disease involves copper metabolism and neurological/hepatic symptoms. Secondary hemochromatosis is iron overload - related, not matching joint findings here.

Answer:

C. Kashin - Beck disease