Question

during a medication reconciliation for a client with active tuberculosis (tb), the nurse notes the client takes pyrazinamide 1000 mg once a day and ibuprofen 600 mg three times a day. what is the priority action the nurse should take? continue with medication administration as prescribed. schedule the doses so that ibuprofen is taken 2 hours after pyrazinamide. notify the provider due to the increased risk of hepatotoxicity. instruct the client to take both medications with food.

Explanation:

Pyrazinamide (used for TB) and ibuprofen (NSAID) both have hepatotoxic potential. Combining them increases the risk of liver damage. Continuing as prescribed ignores the risk. Scheduling timing or taking with food doesn't address the hepatotoxicity risk. Notifying the provider is the priority to assess and manage this risk.

Answer:

C. Notify the provider due to the increased risk of hepatotoxicity.