Question

the doctor orders acyclovir 1,000 mcg iv. the instructions on the vial say to reconstitute with sterile water for a concentration of 0.5 mg/ml and to dilute 1 mg in 50 ml of normal saline. how many milliliters will you administer per dose? (record the answer to the tenth or one decimal place. use a leading zero if it applies. do not use a trailing zero.)

Explanation:

Step1: Convert mcg to mg

Since \(1\ mg = 1000\ mcg\), then \(1000\ mcg=\frac{1000}{1000}mg = 1\ mg\).

Step2: Find the volume from the concentration

The concentration after re - constitution is \(0.5\ mg/mL\). Using the formula \(V=\frac{D}{C}\) (where \(D\) is the dose and \(C\) is the concentration), with \(D = 1\ mg\) and \(C=0.5\ mg/mL\), we have \(V=\frac{1\ mg}{0.5\ mg/mL}=2\ mL\).

Step3: Consider the dilution (if necessary, but in this case, the question asks for the volume to administer per dose from the re - constituted vial. The dilution with normal saline is likely for the infusion process, but the dose calculation from the re - constituted vial is based on the concentration of the re - constituted drug)

The relevant calculation for the volume to administer per dose is based on the re - constituted concentration.

Answer:

\(2.0\)