Question

severe drug - related problem characterized by impaired control over the use of the drug
chemical dependency
drug dependence
sleep disorder
panic disorder
alcohol dependence

Explanation:

Drug dependence is a severe drug - related problem where there is impaired control over drug use. Chemical dependency is a broader term that may involve non - drug chemicals (though often used synonymously with drug dependence in some contexts). Sleep disorder is related to sleep patterns, panic disorder is an anxiety disorder, and alcohol dependence is specific to alcohol. Since the question is about a general drug - related problem (not specific to alcohol) with impaired control over drug use, drug dependence is the most appropriate.

Answer:

drug dependence