Question

why is p53 called a tsg? check all that apply.
check all that apply
it suppresses the growth of abnormal cells.
without it, abnormal cells are more likely to reproduce.
if mutated, cancer is more likely.
it inhibits tumor formation.

Explanation:

Tumor - suppressor genes (TSGs) are genes that help prevent cancer. p53 is a TSG because:

• It suppresses the growth of abnormal cells. This is a key function of tumor - suppressor genes.
• Without it, abnormal cells are more likely to reproduce. Loss of TSG function often leads to uncontrolled cell proliferation.
• If mutated, cancer is more likely. Mutations in TSGs like p53 disrupt their normal tumor - suppressing activity.
• It inhibits tumor formation. This is the overall role of tumor - suppressor genes.

Answer:

• It suppresses the growth of abnormal cells.
• Without it, abnormal cells are more likely to reproduce.
• If mutated, cancer is more likely.
• It inhibits tumor formation.