Question

which pathway explains the development of sickle cell anemia, a condition in which red blood cells have a sickle shape instead of the usual round shape?
incorrect rna translation dna mutation malformed protein incorrect amino acid misshapen red blood cells
dna mutation incorrect rna translation incorrect amino acid malformed protein misshapen red blood cells
malformed protein incorrect rna translation dna mutation incorrect amino acid misshapen red blood cells
dna mutation incorrect amino acid incorrect rna translation malformed protein misshapen red blood cells

Explanation:

Sickle cell anemia is caused by a DNA mutation. This mutation leads to incorrect RNA translation. The incorrect RNA translation results in an incorrect amino acid sequence. The incorrect amino acid sequence causes a malformed protein (abnormal hemoglobin). The malformed protein leads to misshapen (sickle - shaped) red blood cells.

Answer:

B. DNA mutation → Incorrect RNA translation → Incorrect amino acid → malformed protein → misshapen red blood cells