Question

which of the following is an inherited disease of the exocrine cells in which abnormally thick mucus blocks the alveoli, eventually causing death?

emphysema
atelectasis
cystic fibrosis
bronchiectasis

Explanation:

• Emphysema: Usually caused by smoking or long - term exposure to irritants (not an inherited exocrine cell disease).
• Atelectasis: Often due to blockage (e.g., mucus plug, tumor) or compression (e.g., from fluid around the lung), not an inherited exocrine cell disorder.
• Cystic fibrosis: An inherited disorder (autosomal recessive) that affects exocrine cells. The abnormal CFTR protein leads to thick mucus production, which can block alveoli and other ducts (e.g., pancreatic ducts).
• Bronchiectasis: Usually a result of repeated infections or other lung damage (not an inherited exocrine cell disease in the context of the question).

Answer:

cystic fibrosis