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Question
where does the citric acid cycle take place?
The citric acid cycle, also known as the Krebs cycle or tricarboxylic acid (TCA) cycle, is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins into carbon dioxide and chemical energy in the form of guanosine triphosphate (GTP) and adenosine triphosphate (ATP). In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondria. In prokaryotic cells, such as bacteria, which lack mitochondria, the citric acid cycle reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion.
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In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondria. In prokaryotic cells (bacteria), it occurs in the cytosol.