Question

what is the benefit of using a technology called pre-implantation genetic diagnosis?
some parents with disease alleles are now able to have children who do not carry an inherited mutated gene.
embryos undergo gene editing to replace disease alleles.
crispr corrects point mutations in the disease alleles of a human zygote
doctors are able to inform parents whether or not their fetus carries a genetic disease, so they have the option to prepare or abort.

Explanation:

Pre - implantation genetic diagnosis (PGD) is a technique used in in - vitro fertilization (IVF). It involves testing embryos for genetic disorders before they are implanted into the uterus. This allows parents who carry disease alleles (such as in autosomal recessive or autosomal dominant disorders) to select embryos that do not carry the inherited mutated gene.

• Embryos undergoing gene editing to replace disease alleles is more related to gene - editing technologies like CRISPR - Cas9 and is not the main function of PGD.
• CRISPR correcting point mutations in a human zygote is a gene - editing application and not PGD.
• Informing parents about a fetus (after implantation) is prenatal diagnosis, not pre - implantation genetic diagnosis. PGD is done on embryos before implantation.

Answer:

Some parents with disease alleles are now able to have children who do not carry an inherited mutated gene.