Question

watch the animation on autosomal disorders, and then answer the question. inheritance of an autosomal recessive disorder parents (carriers) aa aa non - carrier child a a children a aa aa a aa aa carrier child carrier child affected child in the case of an autosomal dominant disorder, what is the probability of having an affected child if the mother is unaffected and the father is homozygous dominant? 0% 25% 50% 100%

Explanation:

Step1: Determine parental genotypes

Let the dominant allele for the autosomal - dominant disorder be \(A\) and the recessive allele be \(a\). The mother is unaffected, so her genotype is \(aa\). The father is homozygous dominant, so his genotype is \(AA\).

Step2: Set up Punnett - square analysis

When we cross \(AA\times aa\), all of the possible genotypes of the offspring are determined by the combination of the father's and mother's gametes. The father can only produce \(A\) gametes, and the mother can only produce \(a\) gametes.

Step3: Calculate the probability

All of the offspring will have the genotype \(Aa\). Since having the \(A\) allele means being affected in an autosomal - dominant disorder, the probability of having an affected child is 100%.

Answer:

100%