Question

steps in prokaryotic dna replication

order the following stages of dna replication in the proper order from first to last as it occurs in prokaryotic cells.

rank the options below.

two dna molecules, each with one old and one new strand
synthesis of two new dna strands
uncoiling of the parent dna molecule
unzipping the hydrogen bonds between the base pairs

Explanation:

Identify the chronological sequence of replication events

1. Uncoiling of the parent DNA molecule: Topoisomerase (gyrase) and helicase act first to relieve supercoiling and begin unwinding the double helix.
2. Unzipping the hydrogen bonds between the base pairs: Helicase breaks the hydrogen bonds between complementary bases to separate the strands, creating the replication fork.
3. Synthesis of two new DNA strands: DNA polymerase III synthesizes the leading and lagging strands by adding complementary nucleotides.
4. Two DNA molecules, each with one old and one new strand: Replication concludes, resulting in two semiconservative double-stranded DNA molecules.

Answer:

1. Uncoiling of the parent DNA molecule
2. Unzipping the hydrogen bonds between the base pairs
3. Synthesis of two new DNA strands
4. Two DNA molecules, each with one old and one new strand