Question

sickle-cell anemia is the result of a single gene mutation. which cellular protein does this mutation affect?
dna polymerase
fetal hemoglobin
fetal and adult hemoglobin
adult hemoglobin
myoglobin

Explanation:

Sickle - cell anemia is caused by a mutation in the gene that codes for adult hemoglobin. This mutation leads to the production of abnormal hemoglobin (hemoglobin S), which causes red blood cells to sickle. Fetal hemoglobin is not affected in sickle - cell anemia as it has a different structure and is produced during fetal development. DNA polymerase is involved in DNA replication and not related to the hemoglobin defect in sickle - cell anemia. Myoglobin is found in muscle cells and is not the protein affected in this disorder.

Answer:

adult hemoglobin