Question

select the part whose main job is to control which substances enter and leave the cell. cytoplasm centrosome rough endoplasmic reticulum cell membrane submit

Explanation:

The cell membrane is a selectively - permeable barrier. It allows certain substances (like oxygen, nutrients) to enter the cell and waste products to leave the cell while preventing the entry of harmful substances and the exit of essential cellular components.
Cytoplasm is the jelly - like substance within the cell where many cellular processes occur. The centrosome is involved in organizing microtubules and is important for cell division. The rough endoplasmic reticulum is involved in protein synthesis (due to the presence of ribosomes on its surface).

Answer:

cell membrane