Question

question 48
in a karyotype of a male, which of the following would indicate an abnormality?
a total of 46 chromosomes
one x chromosome and one y chromosome
three copies of chromosome 22
22 pairs of autosomes

Explanation:

• A normal human karyotype has 46 chromosomes (22 pairs of autosomes and 1 pair of sex chromosomes).
• Males have one X and one Y chromosome.
• Having three copies of a chromosome (trisomy) is an abnormality.

Answer:

three copies of chromosome 22