Question

question 11
the structural level of a protein least affected by a disruption in hydrogen bonding is the ...
○ primary level.
○ secondary level.
○ tertiary level.
○ quaternary level.

Explanation:

To determine the protein structural level least affected by hydrogen bonding disruption, we analyze each level:

• Primary level: Depends on peptide bonds (covalent) between amino acids, not hydrogen bonds.
• Secondary level: Relies on hydrogen bonds (e.g., α - helices, β - sheets).
• Tertiary level: Involves hydrogen bonds (along with other interactions) for 3D folding.
• Quaternary level: Depends on hydrogen bonds (and other forces) between protein subunits.

Since primary structure is stabilized by covalent peptide bonds, it is least affected by hydrogen bonding disruption.

Answer:

A. primary level.