Question

parkinson’s disease is a brain disorder that may be caused by mutations in several genes that code for the production of alpha-synuclein. individuals who have parkinson’s disease exhibit symptoms such as uncontrollable tremors, difficulty walking, and loss of coordination. how might geneticists determine where the mutations that cause parkinson’s disease are located?

○ pcr analysis
○ gene mapping
○ dna fingerprinting
○ str analysis

Explanation:

To determine where mutations causing Parkinson’s disease are located, we analyze the options:

• PCR analysis amplifies DNA segments, not locate mutations.
• Gene mapping identifies the location of genes (and mutations) on chromosomes, which matches the goal.
• DNA fingerprinting and STR analysis are for identification (e.g., forensic or paternity), not gene location.

Answer:

B. gene mapping