Question

parietal cells antibodies can cause a conditon in which your rbcs become:
a) stacked like coins
b) microcytic
c) stuck together
d) macrocytic
e) nucleated

Explanation:

Parietal cells produce intrinsic factor which is needed for vitamin B12 absorption. Lack of vitamin B12 (due to parietal cell antibodies attacking parietal cells and reducing intrinsic factor) causes megaloblastic anemia. In megaloblastic anemia, red blood cells (RBCs) are macrocytic (larger - than - normal size). Microcytic RBCs are seen in iron - deficiency anemia. RBCs stacked like coins (rouleaux formation) is seen in conditions like multiple myeloma. Nucleated RBCs are usually not present in peripheral blood in adults (except in some severe marrow disorders). RBCs stuck together is a non - specific and less accurate description compared to the other terms in the context of this question.

Answer:

d) macrocytic