Question

multiple choice question which is closest in physical proximity to the nucleic acid of a virus? envelope spike capsid

Explanation:

The capsid is the protein - shell that surrounds the nucleic acid of a virus. The spike is a proteinaceous structure on the surface of the virus envelope (in enveloped viruses) for attachment. The envelope is an outer layer derived from the host - cell membrane in some viruses. The capsid is in direct physical proximity to the viral nucleic acid.

Answer:

capsid