Question

many different types of mutations can occur within the body. tay - sachs disease is a deadly disorder that is caused by a missing codon in the gene coding for production of the hex a enzyme in the body. which type of mutation is responsible for causing tay - sachs disease?
substitution
replacement
insertion
deletion

Explanation:

Tay - Sachs disease is caused by a frameshift mutation. A missing codon (which is a deletion of nucleotides) can cause a frameshift. Substitution and replacement (which is similar to substitution) change one nucleotide for another and usually cause a missense or nonsense mutation (not a frameshift). Insertion adds nucleotides. Deletion removes nucleotides. If a codon (a set of 3 nucleotides) is missing, it is a deletion of 3 nucleotides. But in general, Tay - Sachs is due to a frameshift mutation caused by a deletion (in the HEXA gene, a 4 - base pair deletion in the HEXA gene causes the production of a non - functional hex A enzyme).

Answer:

deletion