Question

epidermal growth factor stimulates proliferation and survival in its target cells. based on your knowledge of cell signaling, put the following steps in order: genes involved in cell growth and proliferation are turned on conformational change in receptor egf binds to its membrane receptor intracellular proteins bind the activated receptor a kinase cascade is initiated this question was created or adapted by your instructor.

Explanation:

Cell signaling begins with the ligand (EGF) binding to its receptor. This binding causes a conformational change in the receptor. Then, intracellular proteins bind the activated receptor. After that, a kinase cascade is initiated. Finally, genes involved in cell growth and proliferation are turned on.

Answer:

1. EGF binds to its membrane receptor
2. conformational change in receptor
3. intracellular proteins bind the activated receptor
4. a kinase cascade is initiated
5. genes involved in cell growth and proliferation are turned on