Question

by dragging and dropping, match the mechanisms of gene regulation in eukaryotes to the correct stage of processing. all choices will be used once. dna primary transcript mrna polypeptide active protein translational control transcriptional control post - translational control post - transcriptional control

Explanation:

• Transcriptional control: This occurs at the DNA - primary transcript stage. It regulates the synthesis of RNA from DNA. For example, factors like transcription factors can bind to DNA near genes and either promote or inhibit the binding of RNA polymerase, which is responsible for transcribing DNA into RNA.
• Post - transcriptional control: Takes place at the primary transcript - mRNA stage. This includes processes such as splicing (removing introns and joining exons), capping (adding a 7 - methylguanosine cap at the 5' end), and polyadenylation (adding a poly - A tail at the 3' end) of the primary transcript to form a mature mRNA.
• Translational control: Happens at the mRNA - polypeptide stage. It can involve regulation of the initiation of translation. For instance, proteins can bind to the mRNA and prevent the ribosome from attaching to the start codon, thus inhibiting translation.
• Post - translational control: Occurs at the polypeptide - active protein stage. This can include processes like protein folding (with the help of chaperones), phosphorylation (adding phosphate groups which can activate or inactivate the protein), and proteolytic cleavage (cutting the polypeptide chain to form the active protein).

Answer:

• DNA - primary transcript: Transcriptional control
• Primary transcript - mRNA: Post - transcriptional control
• mRNA - polypeptide: Translational control
• Polypeptide - active protein: Post - translational control