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Question
if a cells dna is damaged and the cell passes the g, checkpoint anyway, what is most likely to happen? the cell will shrink and die immediately the cell will divide normally the damaged dna may be copied, leading to abnormal cells the cell will permanently stop dividing
The \(G_2\) checkpoint checks for DNA damage and proper DNA replication before mitosis. If DNA is damaged and the cell passes the \(G_2\) checkpoint, during mitosis (cell division), the damaged DNA will be replicated. This replication of damaged DNA can lead to the formation of abnormal cells. Cells that die immediately would likely be due to apoptosis triggered at an earlier checkpoint (like \(G_1\)) if severe damage. A cell dividing normally with damaged DNA at \(G_2\) is unlikely as the checkpoint is supposed to detect damage. A cell permanently stopping dividing (senescence) is more related to other signals (like telomere shortening over multiple divisions) rather than just passing a \(G_2\) checkpoint with damaged DNA.
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The damaged DNA may be copied, leading to abnormal cells.