Question

which issue is related to long-term marijuana use?
brain damage
difficulty thinking
mood swings
altered senses

Explanation:

Long - term marijuana use can lead to brain damage. Difficulty thinking, mood swings, and altered senses can also be associated with marijuana use, but brain damage is a more serious long - term consequence related to the neurotoxic effects of long - term marijuana use on the brain.

Answer:

A. brain damage