Question

which issue is related to long-term heroin use?
○ pleasure
○ depression
○ hypoxia
○ mood swings

Explanation:

Long - term heroin use affects the brain's chemistry and can lead to depression. Pleasure is a short - term effect of heroin use, hypoxia is more related to acute heroin overdose (due to respiratory depression), and mood swings are more associated with substances like stimulants or during withdrawal in some cases, but long - term heroin use is strongly linked to depression.

Answer:

B. depression