Question

what is the most appropriate test to help confirm type 1 diabetes?
a) hgba1c
b) glucose tolerance test
c) serum glucose
d) cbc
e) c - peptide

Explanation:

• HgbA1c: Measures average blood glucose over 2 - 3 months. While useful for monitoring diabetes control, it may not be the most specific for confirming Type 1 diabetes as it can be affected by various factors like anemia.
• Glucose Tolerance Test: Involves measuring blood glucose levels before and after a glucose load. It is more commonly used in the diagnosis of Type 2 diabetes, especially in gestational diabetes.
• Serum glucose: A single serum glucose level can be elevated in many conditions (stress, infection etc.) and is not specific enough to confirm Type 1 diabetes on its own.
• CBC (Complete Blood Count): Measures different components of blood (red blood cells, white blood cells, platelets etc.). It has no direct role in confirming Type 1 diabetes.
• C - Peptide: In Type 1 diabetes, there is destruction of pancreatic beta cells. C - Peptide is a by - product of insulin production. Low C - Peptide levels (since insulin production is impaired in Type 1 diabetes) help in confirming the diagnosis of Type 1 diabetes.

Answer:

e) C - Peptide