Question

what determines the 3-d shape of an enzyme?

Explanation:

Enzymes are proteins. The primary structure (amino acid sequence) of a protein determines its 3 - D shape. Different amino acids interact (e.g., via hydrogen bonds, disulfide bridges, hydrophobic interactions) based on their sequence, folding the protein into its specific 3 - D conformation.

Answer:

The amino acid sequence (primary structure) of the enzyme determines its 3 - D shape.