Question

us district courts hear federal cases involving
state and local issues.
civil and state issues.
civil and criminal issues.
criminal and international issues.

Explanation:

US District Courts are the general trial courts of the federal court system. They have jurisdiction over both civil and criminal cases that fall under federal law. State and local issues (first option) are mainly handled by state courts. Civil and state issues (second option) mix federal (civil cases under federal law) with state - which is not the main focus. Criminal and international issues (fourth option) - international issues are more specialized and not the core of District Court's general federal case jurisdiction.

Answer:

civil and criminal issues.