Question

question 36 (1 point)
rifampin blocks:
transcription
translation
peptidoglycan synthesis
membrane integrity
question 37 (1 point)
sulfonamides work by:
destroying membranes
breaking peptide bonds
blocking ribosomal trna binding
mimicking paba and blocking folic acid synthesis

Explanation:

• Question 36: Rifampin is an antibiotic that inhibits bacterial RNA polymerase. RNA polymerase is crucial for transcription (the process of synthesizing RNA from a DNA template). So, rifampin blocks transcription.
• Question 37: Sulfonamides are competitive inhibitors of dihydropteroate synthase. PABA (para - aminobenzoic acid) is a substrate for dihydropteroate synthase in the folic acid synthesis pathway. Sulfonamides mimic PABA, bind to dihydropteroate synthase, and prevent the synthesis of dihydrofolic acid (a precursor of folic acid). Folic acid is essential for nucleotide synthesis (required for DNA replication).

Answer:

• Question 36: Transcription
• Question 37: Mimicking PABA and blocking folic acid synthesis