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which sentence describes a substitution error that could occur during dna replication?
a. a cytosine is added where an adenine is supposed to be in the growing strand.
b. a cytosine is left off the growing strand where a cytosine was supposed to be added.
c. a cytosine is added to the template strand when it was supposed to be added to the growing strand.
d. two cytosine bases are added where a single cytosine was supposed to be in the growing strand.
Define substitution mutations
A substitution mutation is a type of replication error where one nucleotide base is replaced by another. In Gene Mutations, this means a single incorrect base is incorporated into the newly synthesized strand in place of the correct base.
Analyze the given options
- Option A: "A cytosine is added where an adenine is supposed to be in the growing strand." This describes replacing one base (adenine) with another (cytosine), which is a substitution.
- Option B: "A cytosine is left off..." This describes a deletion error.
- Option C: "A cytosine is added to the template strand..." Replication adds bases to the growing strand, not the template strand.
- Option D: "Two cytosine bases are added..." This describes an insertion error.
Identify the correct choice
Based on the definitions of DNA Replication Errors, replacing one base with another is a substitution. Therefore, Option A is the correct description.
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- (A) A cytosine is added where an adenine is supposed to be in the growing strand. (Correct answer)
- (B) A cytosine is left off the growing strand where a cytosine was supposed to be added.
- (C) A cytosine is added to the template strand when it was supposed to be added to the growing strand.
- (D) Two cytosine bases are added where a single cytosine was supposed to be in the growing strand.