Question

a patient is taking carbamazepine for seizures. which of the following may increase its effects? dairy products grapefruit juice lettuce fatty foods grapefruit juice which drug recall is classified as one in which there is a reasonable probability that the use of the medication will cause or lead to a serious adverse event or even death? class i class ii class iii class iv

Explanation:

1. Grapefruit juice can inhibit the cytochrome - P450 enzymes in the liver that are involved in the metabolism of carbamazepine. This inhibition leads to decreased metabolism of carbamazepine, resulting in increased blood levels and thus increased effects of the drug.
2. Class I drug recalls are the most serious type of drug recalls. They are issued when there is a reasonable probability that the use of the medication will cause or lead to a serious adverse event or even death.

Answer:

1. Grapefruit juice
2. Class I