Question

a nurse is reviewing the medical record of a client who has a prescription for probenecid to treat gout. the nurse should identify that which of the following medications can interact with probenecid?

• colchicine
• naproxen
• aspirin
• prednisone

Explanation:

Probenecid is a uricosuric agent used for gout. Aspirin (salicylates) can interfere with probenecid's uricosuric action by competing for renal tubular transport, reducing probenecid's effectiveness. Colchicine, naproxen, and prednisone do not have this specific interaction with probenecid.

Answer:

Aspirin